Inhibition of Hippo pathway signalling reverses systolic heart failure

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منابع مشابه

The Prevalence of Anemia in Elderly With Systolic Heart Failure

Objectives: Anemia is prevalent in heart failures and is an independent risk factor for adverse clinical outcomes in patients with CHF. The aim of the present study was to determine the prevalence of anemia in elderly with systolic heart failure hospitalized in Alborz Hospital of Karaj in 2009. Methods & Materials: This is a descriptive retrospective study that reviewed 154 medical records o...

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Background and Purpose: To improve life quality, and lower mortality and rehospitalization for heart failure patients, awareness and adherence to self-care behaviors are essential. This study aims to determine the adherence level to self-care behaviors in the patients with systolic heart failure hospitalized in Alborz hospital in Karaj andShahriar hospital, and it was conducted in 2013. Methods...

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Copyright © 2010 Massachusetts Medical Society. A 74-year-old man with a history of hypertension and myocardial infarction that occurred 5 years previously presents with breathlessness on exertion. His current medications include a statin and aspirin. On examination, his pulse is 76 beats per minute and regular, and his blood pressure is 121/74 mm Hg. There is jugular venous distention, lateral...

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Emerging role of Hippo signalling pathway in bladder cancer

Bladder cancer (BC) is one of the most common cancers worldwide with a high progression rate and poor prognosis. The Hippo signalling pathway is a conserved pathway that plays a crucial role in cellular proliferation, differentiation and apoptosis. Furthermore, dysregulation and/or malfunction of the Hippo pathway is common in various human tumours, including BC. In this review, an overview of ...

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Advances in systolic heart failure

Heart failure due to systolic dysfunction has enormous global impact. Medical management based on an understanding of the pathophysiology of the disease as well as its neurohormonal mechanisms has greatly advanced over the past 25 years. Below is a review of recent and emerging data on epidemiology and diagnosis of heart failure due to systolic dysfunction and the current and future management ...

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ژورنال

عنوان ژورنال: Nature Reviews Cardiology

سال: 2017

ISSN: 1759-5002,1759-5010

DOI: 10.1038/nrcardio.2017.166